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25 Jan 2018
ABSTRACT: Invasive candidiasis is among the most life-threatening infections in patients in intensive care units. Although Candida albicans is the leading cause of candidaemia, the incidence of Candida parapsilosis infections is also rising, particularly among the neonates. Due to differences in their biology, these species employ different antifungal resistance and virulence mechanisms and also ...
25 Jan 2018
ABSTRACT: RNA molecules play important roles in virtually every cellular process. These functions are often mediated through the adoption of specific structures that enable RNAs to interact with other molecules. Thus, determining the secondary structures of RNAs is central to understanding their function and evolution. In recent years several sequencing-based approaches have been developed that ...
15 Jan 2018
ABSTRACT: Candida spp. are leading causes of opportunistic mycoses, including life-threatening hospital-borne infections, and novel antifungals, preferably aiming targets that have not been used before, are constantly needed. Hydrazone- and guanidine-containing molecules have shown a wide range of biological activities, including recently described excellent antifungal properties. In this study, ...
12 Jan 2018
ABSTRACT: Online sequence databases such as NCBI GenBank serve as a tremendously useful platform for researchers to share and reuse published data. However, submission systems lack control for errors such as organism misidentification, which once entered in the database can be propagated and mislead downstream analyses. Here we present an illustrating case of misidentification of Candida albicans ...
7 Nov 2017
ABSTRACT: Candida albicans is a dimorphic commensal fungus that causes severe oral infections in immunodeficient patients. Invasion of C. albicans hyphae into oral epithelium is an essential virulence trait. Interleukin-17 (IL-17) signaling is required for both innate and adaptive immunity to C. albicans . During the innate response, IL-17 is produced by γδ T cells and a poorly understood ...
6 Sep 2017
The OPATHY newsletter informs about latest activities in the network. It will appear every 3 months. You can register to receive it automatically.
4 Sep 2017
The second OPATHY Annual Meeting/ Summer School took place from 27th of August till 1st of September at Hans-Knoell-Institute in Jena, Germany.
4 Aug 2017
During the HFP2017 conference in La-Colle-Sur-Loupe, France, OPATHY scientific advisory board member Judith Berman (Tel Aviv University) was interviewed by OPATHY ESR Elise Iracane (University College Dublin).
6 Jul 2017
ABSTRACT: Hybridization between different species can result in the emergence of new lineages and adaptive phenotypes. Occasionally, hybridization in fungal organisms can drive the appearance of opportunistic lifestyles or shifts to new hosts, resulting in the emergence of novel pathogens. In recent years, an increasing number of studies have documented the existence of hybrids in diverse yeast ...
24 Mar 2017
The 2017 MCAA Conference and General Assembly will be held on Friday 24th and Saturday 25th March 2017 in Salamanca, Spain. The host for this event is the University of Salamanca, in cooperation with the MCAA Spain/Portugal Chapter. The winner of the BCN Science Slam will present on a Science Slam which will take place on 24th of March as a side program of the MCAA general assembly meeting.